Successful projects demand reliable protein. We are completely obsessed with Gene to Structure strategies and can't wait to help you tackle your most significant protein production challenges.
1. Protein Engineering
- Rational Construct Design
- Directed Evolution
- Solubility Tags Panels
- Isotope Labeling (15N, 13C)
- Custom conjugation (biotinylation)
2. Protein Expression
- Small Scale Expression Scouting
- ~E.Coli
- ~Insect
- ~Mammalian
- ~Yeast
- Large Scale Expression Workflows
- Antigen Production
- Antibody and nanobody production
- Endotoxin free production suites for animal studies
- Protein Refolding
- Challenging Purifications Workflows
- ~RNA binding proteins
- ~Intrinsically disordered proteins
- ~Membrane proteins
- ~VLP Technology
3. Protein Purification
- Comprehensive NGC Chromatography Platform
- Affinity chromatography
- Ion-exchange chromatography
- Size-exclusion chromatography
- Hydrophobic interaction chromatography
- Reversed phase chromatography
4. Large Scale Purification Workflows
- ChromLab™ software scouting workflows (pH,resin,%B)
- Tangential flow filtration (TFF)/Diafiltration
- Endotoxin free production suites for animal studies
- VLP Technology
5. Extensive protein characterization and QC
- Purity and concentration SDS (reduced/non-reduced)
- Analytical size Exclusion (aSEC)
- Intact Mass
- Aggregation (DLS)
- Thermostability
- PTM analysis
- Peptide mapping